1,3,4-Oxadiazol-2(3H)-one formation from N-acylaminobiurets and related compounds and from S-benzyl 3-acyl(thiocarbazates)
Abstract
The formation of 1,3,4-oxadiazol-2(3H)-ones by thermal cyclisation of 1-acylsemicarbazides has been shown to occur with equal facility by use of readily available N-acylaminobiurets. Cyclisation by thermolysis of S-benzyl 3-acylcarbazates also proceeds smoothly though in lower yields.