Issue 0, 1982
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Studies on organic fluorine compounds. Part 37. Studies on steroids. Part 78. Synthesis of 24,24-difluoro- and 24ξ-fluoro-25-hydroxyvitamin D3

Yoshiro Kobayashi,   Takeo Taguchi,   Tadafumi Terada,   Jun-ichi Oshida,   Masuo Morisaki  and  Nobuo Ikekawa  

Abstract

To clarify the physiological significance of C-24 hydroxylation in vitamin D3 metabolism, vitamin D3 compounds blocked at C-24 by fluorine substituents, namely 24,24-difluoro-25-hydroxyvitamin D3(1) and 24ξ-fluoro-25-hydroxyvitamin D3(2) have been synthesized from 3β-hydroxychol-5-en-24-oic acid (13).

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Article information

DOI
https://doi.org/10.1039/P19820000085
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1982, 85-91

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Studies on organic fluorine compounds. Part 37. Studies on steroids. Part 78. Synthesis of 24,24-difluoro- and 24ξ-fluoro-25-hydroxyvitamin D3

Y. Kobayashi, T. Taguchi, T. Terada, J. Oshida, M. Morisaki and N. Ikekawa, J. Chem. Soc., Perkin Trans. 1, 1982, 85 DOI: 10.1039/P19820000085

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