Issue 21, 1982

Reduction of steroid 17-ketones by enantiomeric chiral reducing agents

Abstract

The reduction of steroid 17-ketones by a chiral hydrosilane–rhodium–(–)(2S,3S)-O-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane reagent allows greater stereoselectivity of 17α-alcohol formation than is obtained by other methods.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1982, 1238-1239

Reduction of steroid 17-ketones by enantiomeric chiral reducing agents

G. Göndös and J. C. Orr, J. Chem. Soc., Chem. Commun., 1982, 1238 DOI: 10.1039/C39820001238

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements