Racemisation-free esterification of 2-nitrohenylsulphenyl-protected amino-acids by dicyclohexylcarbodi-imide-4-dimethylaminopyridine
Abstract
Racemisation during esterification of N-protected amino-acids by dicyclohexylcarbodi-imide–4-dimethylaminopyridine (DCC–DMAP) can be avoided by use of the 2-nitrophenylsulphenyl(Nps) protecting group.