Treatment with acids converted N-(2-hydroxy-2-Phenethyl)-2-aminomethylthiophens into thienotetrahydro-pyridines in good yield; with trifluoroacetic acid the major product was the rearranged 7-phenyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine, whereas with polyphosphoric acid the product formed exclusively was the non-rearranged 4- phenyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine.
C. Mackay and R. D. Waigh, J. Chem. Soc., Chem. Commun., 1982, 793 DOI: 10.1039/C39820000793
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