Co-enzyme Q10 was efficiently synthesised by stereo-and regio-selective prenylation of the protected hydroquinone (2) with isoprene epoxide and solanesyl p-tolyl sulphone in good overall yield.
K. Sato, O. Miyamoto, S. Inoue, T. Yamamoto and Y. Hirasawa, J. Chem. Soc., Chem. Commun., 1982, 153 DOI: 10.1039/C39820000153
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