Issue 0, 1981

Michael addition to trans-enediones: a facile route to 2,3,4,5-tetra-substituted furans

Abstract

The enediones (2) are useful starting materials for a two-step synthesis of tetrasubstituted furans, which are not otherwise easily available. Michael addition of active methylene compounds to the enediones (2) led to the two regioisomeric adducts (8) and (9), which then cyclized to furans under very mild conditions.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1981, 2398-2400

Michael addition to trans-enediones: a facile route to 2,3,4,5-tetra-substituted furans

R. Antonioletti, M. D'Auria, G. Piancatelli and A. Scettri, J. Chem. Soc., Perkin Trans. 1, 1981, 2398 DOI: 10.1039/P19810002398

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