The known hydroxy-aldehyde (5) has been converted into 6β-decarboxyprostaglandin I1(19) and 6β-prostaglandin I1(3) by (i) reaction with an appropriate organometallic reagent, (ii) cyclisation via the intermediate formation of an iodonium ion, and (iii) hydrodeiodination and desilylation.
M. A. W. Finch, S. M. Roberts and R. F. Newton, J. Chem. Soc., Perkin Trans. 1, 1981, 1312 DOI: 10.1039/P19810001312
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