Issue 0, 1981

Synthesis of (±)-6β-prostaglandin I1 and (±)-6β-decarboxyprostaglandin I1

Abstract

The known hydroxy-aldehyde (5) has been converted into 6β-decarboxyprostaglandin I1(19) and 6β-prostaglandin I1(3) by (i) reaction with an appropriate organometallic reagent, (ii) cyclisation via the intermediate formation of an iodonium ion, and (iii) hydrodeiodination and desilylation.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1981, 1312-1316

Synthesis of (±)-6β-prostaglandin I1 and (±)-6β-decarboxyprostaglandin I1

M. A. W. Finch, S. M. Roberts and R. F. Newton, J. Chem. Soc., Perkin Trans. 1, 1981, 1312 DOI: 10.1039/P19810001312

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