Synthesis and determination of the configuration of 23,25-dihydroxy-vitamin D3; a new metabolite of vitamin D3; X-ray crystal structure of a 3,23,25-triol precursor
Abstract
The configuration at the C-23 position of 23,25-dihydroxyvitamin D3, a new metabolite of vitamin D3, was determined as S by comparison with the synthetically prepared C-23 S- and R-isomers and an X-ray crystal-lographic determination of the structure of the 3,23, 25-triol (7b).