An enantioselective route to both the (+)- and (–)-enantiomers of the Aspidosperma-type indole alkalloid, quebrachamine, has been established using a single chiral lactone obtained from L-glutamic acid or D-mannitol.
S. Takano, M. Yonaga and K. Ogasawara, J. Chem. Soc., Chem. Commun., 1981, 1153 DOI: 10.1039/C39810001153
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