Stereospecific intramolecular addition of α-lithio sulphoxides or sulphones to inactivated double bonds
Abstract
Treatment of the l-oxides or l,l-dioxides of trans homoallylic 8–10 membered ring cyclic sulphides with BuLi in tetrahydrofuran result in transsnnular addition of the α-thio carbanion to the E double bond with formation of bicyclic products.