Biosynthetic incorporation of cyclo-(L-phenylalanyl-L-phenylalanyl) into bisdethiobis(methylthio)acetylaranotin in Aspergillus terreus
Abstract
cyclo-(L-[15N] Phenylalanyl-L-[1-13C] phenylalanyl) was incorporated intact into bisdethiobis (methyl-thio) acetylaranotin (1) in Aspergillus terreus, the presence of doubly labelled species in the product being detected by 13C n.m.r. spectroscopy (JCN 13 Hz)