Issue 11, 1981

Mechanism of direct side-chain acylamination and aminoarylation of 2- and 4-picoline 1-oxides

Abstract

The isolation of radical coupling products and the observation of appropriate C.I.N.D.P. signals suggest that most of the title reactions proceed by homolysis of the anhydro-bases (4) or (9) followed by radical recombinations; a diaza-oxy-Cope rearrangement may still account for the formation of α-acylamination products.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1981, 561-562

Mechanism of direct side-chain acylamination and aminoarylation of 2- and 4-picoline 1-oxides

R. A. Abramovitch, D. A. Bramovitch and P. Tomasik, J. Chem. Soc., Chem. Commun., 1981, 561 DOI: 10.1039/C39810000561

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