An unequivocal synthesis of 1-benzyl-3-ethyl-1,6-dihydropyridine and its use for a biogenetically modelled synthesis of (±)-catharanthine
Abstract
The first unambiguous synthesis of an N-substituted 3-ethyl-1,6-dihydropyridine (2) and its use for a biomimetic synthesis of (±)-catharanthine (4) are described.