Preparation and reactions of 1-lithio-oxy-1-lithio-amino-allene derivatives
Abstract
The title compounds Li2+[R2CHC
C(–Ō)NR1], prepared from secondary α-keto-amides via the Shapiro reaction, reacted at C-2 with aldehydes, acetone, and deuterium oxide; the products [R2CH
C(CONHR1)C(OH)R4R5] were intermediates for the synthesis of substituted 3-methylenetetrahydrofuran-2-ones.