Determination of dithiocarbamates by liquid chromatography using transition-metal salts as “ion-pair” reagents

Abstract

A technique has been developed for the liquid-chromatographic determination on an octadecylsilyl silica reversed-phase column of N-alkyl- and NN-dialkyldithiocarbamates by adding transition-metal salts of cobalt(II) or nickel(II) to the mobile phase. The unsuccessful use of mercury(II), copper(II) and lead(II) is discussed and the mixed complexes formed when two dithiocarbamates are injected are described. The retentions of the dithiocarbamates are compared with those of related thiuram disulphides.