Hydrogen exchange at the unsubstituted positions in 1,2,5-trimethyl- and 1,3,4-trimethyl-pyrrole in aqueous buffer has been examined. The two positions were found to be of similar reactivities. General acid catalysis was detected. No hydrogen exchange on the methyl groups of 2,3,4,5-tetramethylpyrrole, even in strong acid, was detected. The 13C n.m.r. spectrum of the tetramethylpyrrole was examined.
R. S. Alexander and A. R. Butler, J. Chem. Soc., Perkin Trans. 2, 1980, 110 DOI: 10.1039/P29800000110
To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.
If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.
If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.
Read more about how to correctly acknowledge RSC content.
Please wait while we load your content...