A eudesmane-type sesquiterpene acid with an aromatic A-ring isolated from a Guyanan tree Dulacia guianensis(Olacacea) was assigned a structure and an absolute stereochemistry (1) on the basis of spectroscopic evidence and partial synthesis. The isolate had moderate antileukaemic activity in P–388 lymphocytic leukaemia.
J. Polonsky, Z. Varon, H. Jacquemin, D. M. X. Donnelly and M. J. Meegan, J. Chem. Soc., Perkin Trans. 1, 1980, 2065 DOI: 10.1039/P19800002065
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