Preparation of 4-[alkyl-(or aryl)-thio-substituted]-1,4-dihydropyridines and their use as thiolate-transferring agents
Abstract
Alkane-(or arene)-thiols or thiolates add smoothly to esters or amides of 1-methylpyridinium-3,5-dicarboxylic acid salts; on treatment of these adducts with activated acid-derivatives, thioesters are formed in excellent yields.