5-Endo-trig cyclisation and 1,3-anionic cycloaddition in arylimine derivatives of α-amino acid esters
Abstract
Michael adducts of imines of α-amino acid esters are converted into a mixture of two stereoisomeric pyrrolidines by benzyltrimethylammonium methoxide (BTAM) apparently by a 5-endo-trig cyclisation.