A new synthesis of formycin via nitropyrazole derivatives
Abstract
3-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)pyrazole (4) has been converted into formycin (15) by a sequence involving, as the key step, cine substitution, by cyanide ion, of the 1-nitro group in the 1,4-dinitropyrazole (10).