Issue 0, 1979

Biosynthesis of malonomicin. Part 1. 13C nuclear magnetic resonance spectrum and feeding experiments with 13C-labelled precursors

Abstract

The 13C·n.m.r. spectrum of malonomicin (1) has been completely assigned. The biosynthesis of malonomicin was studied in Streptomyces rimosus by feeding experiments with 13C-labelled precursors. Evidence is presented that malonomicin is derived from 2, 3-diaminopropanoic acid, one molecule of acetate, a C4-dicarboxylic acid (presumably succinic acid), CO2, and serine.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1979, 2017-2022

Biosynthesis of malonomicin. Part 1. 13C nuclear magnetic resonance spectrum and feeding experiments with 13C-labelled precursors

D. Schipper, J. L. van der Baan and F. Bickelhaupt, J. Chem. Soc., Perkin Trans. 1, 1979, 2017 DOI: 10.1039/P19790002017

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