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Issue 11, 1979
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Trimethylsilyl iodide as a peptide deblocking agent

Abstract

Removal of urethane and benzyl ether blocking groups from peptides is readily accomplished by treatment with trimethylsilyl iodide which is particularly useful for the debenzylation of O-benzyltyrosine without the formation of rearrangement products.

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Article type: Paper
DOI: 10.1039/C39790000495
Citation: J. Chem. Soc., Chem. Commun., 1979,0, 495-496
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    Trimethylsilyl iodide as a peptide deblocking agent

    R. S. Lott, V. S. Chauhan and C. H. Stammer, J. Chem. Soc., Chem. Commun., 1979, 0, 495
    DOI: 10.1039/C39790000495

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