The factors affecting the reversibility and energetics of competing reaction pathways are discussed and shown to provide a rational explanation for the regioselectivity of reaction of 2-substituted cyclohexanone enamines.
P. W. Hickmott and N. F. Firrell, J. Chem. Soc., Perkin Trans. 1, 1978, 340 DOI: 10.1039/P19780000340
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