Two micromethods for determining the linkage of adducts formed between polyaromatic hydrocarbons and nucleic acid bases
Abstract
Two micromethods, one based on c.d.–pK measurements and the other on Fourier transform i.r. spectroscopy, for determining the linkage of adducts formed between polyaromatic hydrocarbons and nucleic acid bases are described; both methods can be performed on the microgram scale, in contrast to other spectroscopic methods which require larger quantities of sample.