SCHEDULED MAINTENANCE
The epoxyacetal (2) is ring opened by appropriate organometallic reagents regioselectively to afford the acetals (15) and (17) in high yield; the acetal (15) was transformed into the prostaglandin-F2α precursor (4) in two steps, while (17) furnished the prostaglandin-E2 intermediate (24) in three steps.
R. F. Newton, C. C. Howard, D. P. Reynolds, A. H. Wadsworth, N. M. Crossland and S. M. Roberts, J. Chem. Soc., Chem. Commun., 1978, 662 DOI: 10.1039/C39780000662
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