Issue 8, 1978

Alternative synthetic route to the cembrene skeleton

Abstract

The cembrene derivative (VI; Z = SO2Ph) has been prepared by coupling of the geranyl units (I) and (II) to give the seco-cembrene derivatives (IIIa) or (IIIb), followed by reduction (IIIa) or hydrolysis (IIIb), conversion into the bromide, (V; Y = Br), and ring closure with lithium di-isopropylamide.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1978, 359-360

Alternative synthetic route to the cembrene skeleton

H. Takayanagi, T. Uyehara and T. Kato, J. Chem. Soc., Chem. Commun., 1978, 359 DOI: 10.1039/C39780000359

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