Issue 5, 1978

Cycloguanil hydrochloride: X-ray crystal structure of the antifolate drug

Abstract

The important antimalarial drug cycloguanil shares the following features with other antifolate agents studied crystallographically: (i) protonation at N(3), and (ii) a phenyl ring nearly perpendicular to the heterocycle.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1978, 188-190

Cycloguanil hydrochloride: X-ray crystal structure of the antifolate drug

C. H. Schwalbe and W. E. Hunt, J. Chem. Soc., Chem. Commun., 1978, 188 DOI: 10.1039/C39780000188

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements