Synthesis of analogues of bradykinin with replacement of the arginine residues by 4-guanidinophenyl-L-alanine
Abstract
The synthesis is described of three analogues of bradykmin in which the terminal arginine residues were separately or together replaced by 4-guanidinophenyl-L-alanine. The analogues were considerably less potent than the parent peptide in their action on smooth muscle in vitro