Issue 9, 1977

Total synthesis of thiazolinone analogues of indolmycin

Abstract

The synthesis of thiazolinone analogues of the naturally occurring oxazolinone antibiotic indolmycin is described. Relative reactivities of isomeric intermediates, rearrangements, and the stereochemistry of products, are explained by a mechanism involving an indole-3-spirocyclopropylium ion.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1977, 1012-1018

Total synthesis of thiazolinone analogues of indolmycin

M. R. Harnden and N. D. Wright, J. Chem. Soc., Perkin Trans. 1, 1977, 1012 DOI: 10.1039/P19770001012

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements