Issue 5, 1977

Synthesis of 2-(p-nitrophenoxy)ethylamine and its N-alkyl, N-aryl, and 1,1-dimethyl derivatives

Abstract

2-(p-Nitrophenoxy)ethylamines have been prepared by reactions of 2-aminoethanols (as oxygen nucleophiles) with p-chloronitrobenzene and by base-catalysed Smiles rearrangement of N-(2-hydroxyethyl)-p-nitrobenzene-sulphonamides in aqueous acetone or in methylene chloride containing 18-crown-6-complexed potassium hydroxide.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1977, 581-583

Synthesis of 2-(p-nitrophenoxy)ethylamine and its N-alkyl, N-aryl, and 1,1-dimethyl derivatives

A. C. Knipe, N. Sridhar and J. Lound-Keast, J. Chem. Soc., Perkin Trans. 1, 1977, 581 DOI: 10.1039/P19770000581

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