Issue 24, 1977

Total synthesis of clavulanic acid analogues via isomerisation of 7-oxo-4-oxa-1-azabicyclo[3.2.0]hept-2-enes

Abstract

Sodium Z-3-benzylidene-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate (1b), a novel clavulanic acid analogue, has been prepared via the isomerisation of the bicycloheptane (2a).

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1977, 905b-906

Total synthesis of clavulanic acid analogues via isomerisation of 7-oxo-4-oxa-1-azabicyclo[3.2.0]hept-2-enes

P. H. Bentley, G. Brooks, M. L. Gilpin and E. Hunt, J. Chem. Soc., Chem. Commun., 1977, 905b DOI: 10.1039/C3977000905B

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