Issue 22, 1977

Oxidation of clavulanic acid and a ready synthesis of the 7-oxo-4-oxa-1-azabicyclo[3.2.0]hept-2-ene ring system

Abstract

Pyridinium chlorochromate oxidation of benzyl clavulanate gave the Z- and E-aldehydes (3) and (4), whereas attempted Pfitzner–Moffat oxidation resulted in the formation of the diene (5).

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1977, 808a-808a

Oxidation of clavulanic acid and a ready synthesis of the 7-oxo-4-oxa-1-azabicyclo[3.2.0]hept-2-ene ring system

D. F. Corbett, T. T. Howarth and I. Stirling, J. Chem. Soc., Chem. Commun., 1977, 808a DOI: 10.1039/C3977000808A

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