Diketen as a butenoic acid synthon in regioselective olefin syntheses
Abstract
The adduct (2) between diketen (1) and Me3SiCH2MgCl is a versatile methylbutenoic (isoprenoid) acid synthon in allylation with prenyl bromide, in δ-lactone formation with several carbonyl compounds, and in palladium-mediated alkylation.