Oestradiol and oestrone can be covalently bonded to DNA as a result of oxidation by iodine or hydrogen peroxide and, alternatively, by incubation with a rat liver microsomal preparation in vitro: radioisotope studies show that these processes are mechanistically distinct.
G. M. Blackburn, L. Orgee and G. M. Williams, J. Chem. Soc., Chem. Commun., 1977, 386 DOI: 10.1039/C39770000386
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