Issue 9, 1977

Enantioselective reduction of racemic ketones by yeast

Abstract

Selective reductions of one enantiomer of simple racemic ketones have been observed with actively fermenting yeast; the method, which readily yields an optically active secondary alcohol and the recovered ketone in optically pure form, has led to the preparation of optically active sulphoxides and α-chloroketones.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1977, 315-316

Enantioselective reduction of racemic ketones by yeast

R. L. Crumbie, D. D. Ridley and G. W. Simpson, J. Chem. Soc., Chem. Commun., 1977, 315 DOI: 10.1039/C39770000315

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