Hemin C (2) was prepared in 45–50% yield by the reduction of a solution of iron protopophyrin IX [hemin (1)] and L-cysteine with sodium borohydride in the presence of oxygen and cetyltrimethylammonium bromide micelle.
S. Kojo and S. Sano, J. Chem. Soc., Chem. Commun., 1977, 249 DOI: 10.1039/C39770000249
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