The aminomethylbilane corresponding to head-to-tail combination of four porphobilinogen units is unambiguously synthesised and it is converted (rearranged) by the deaminase–cosynthetase enzyme system into uro'gen-III, the precursor of the natural porphyrins, chlorins, and corrins; 13C-labelling establishes the specificity of the conversion.
A. R. Battersby, E. McDonald, D. C. Williams and H. K. W. Wurziger, J. Chem. Soc., Chem. Commun., 1977, 113 DOI: 10.1039/C39770000113
To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.
If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.
If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.
Read more about how to correctly acknowledge RSC content.
Please wait while we load your content...