Preparation of the eight monohydroxydibenz[b,f][1,4]oxazepin-11(10H)-ones

Abstract

The eight possible isomeric monohydroxydibenz[b,f][1,4]oxazepin-11(10H)-ones have been prepared and their mass spectra determined. With the exception of the 7-hydroxy-derivative the fragmentation patterns of the isomers were similar, although the relative line intensities allowed distinctions between the isomers to be made. The syntheses of several irritant monomethoxydibenz[b,f][1,4]oxazepines are also described.