SCHEDULED MAINTENANCE
When hydroxylamine reacts with 1-methyl-cytosine or with 1,3-dimethylcytosine in D2O solution, partial deuteriodeprotonation is observed at position-5 in both products and to a greater extent in methylcytosines which had not reacted thereby showing that hydroxyl-amine addition across the pyrimidine 5,6-double bond is reversible and is only partly stereospecific.
G. M. Blackburn, V. C. Solan, D. M. Brown and P. F. Coe, J. Chem. Soc., Chem. Commun., 1976, 724 DOI: 10.1039/C39760000724
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