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6-Tritiobenzo[a]pyrene has been prepared from 6-iodobenzo[a]pyrene via lithiation and reaction with tritiated water: photochemical binding of this material to DNA resulted in the loss of 92% of its tritium content while binding using rat liver microsomes showed a loss of only 20% of tritium.
G. M. Blackburn, G. M. Milne and L. Orgee, J. Chem. Soc., Chem. Commun., 1976, 359 DOI: 10.1039/C39760000359
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