Regiospecific syn-elimination from the acid-catalysed reactions of 9-hydroxy-10-methyldecahydronaphthalenes
Abstract
The H2SO4–HOAc–Ac2O catalysed dehydration of 9-hydroxy-10-methyl-cis- and trans-decahydronaphthalenes occurs regiospecifically without skeletal or methyl rearrangement and is interpreted in terms of the intermediacy of a tight ion pair where the departing oxyanion acts as the base in the removal of a syn-proton.