The positive charge in [H2N(CH2)3NMe3]+ makes this amine a particularly effective catalyst for the acid dissociation of chloroform, and general base catalysis of this reaction in dilute aqueous buffer solutions of this amine is therefore easily detectable.
D. B. Dahlberg, A. J. Kresge and A. C. Lin, J. Chem. Soc., Chem. Commun., 1976, 35 DOI: 10.1039/C39760000035
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