The kinetics and mechanism of the electrophilic substitution of heteroaromatic compounds. Part XLVIII. Nitration of pyrazoles in the 3- and 5-positions
Abstract
The kinetics of nitration of 1,4-dimethyl- and 4-methyl-1-p-nitrophenylpyrazole at the 3-position, and of 1,4-dimethyl-3-nitropyrazole at the 5-position show that these reactions all proceed on free base species. Standard rate constants (ko) are calculated and compared with those for the nitration of related compounds.