A new rearrangement of ketonic nitrones; a convenient alternative to the Beckmann rearrangement
Abstract
Ketonic nitrones are smoothly transformed by treatment with toluene-p-sulphonyl chloride in pyridine in the presence of some water into N-alkyl amides. The regiospecificity, stereospecificity, and mechanism of this new reaction have been investigated. The overall procedure provides a convenient alternative to the Beckmann rearrangement.