The chemical degradation of oligopeptides to cyclic dipeptides and identification of the latter by gas chromatography–mass spectrometry has been investigated as a method of amino-acid sequencing. Advantages and disadvantages of the method are described.
R. A. W. Johnstone and T. J. Povall, J. Chem. Soc., Perkin Trans. 1, 1975, 1297 DOI: 10.1039/P19750001297
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