Issue 9, 1975

Reaction of dimethyl imidazole-4,5-dicarboxylate with styrene oxide

Abstract

The reaction between the potassium salt of dimethyl imidazole-4,5-dicarboxylate and styrene oxide is shown to produce 4-methoxycarbonyl-1-styrylimidazole-5-carboxylic acid or methyl 5,6-dihydro-8-oxo-6-phenyl-8H-imidazo[5,1-c][1,4]oxazin-1-carboxylate. The subsequent cleavage of this lactone and the use of styrene [18O]oxide indicate the intermediacy of the lactone in the formation of the styryl acid.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1975, 798-803

Reaction of dimethyl imidazole-4,5-dicarboxylate with styrene oxide

G. Cooper and W. J. Irwin, J. Chem. Soc., Perkin Trans. 1, 1975, 798 DOI: 10.1039/P19750000798

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements