Isomerisation of 1,2,3,4,5,8-hexahydroisoquinolines to hexahydroisoquinolines containing a 1,3-diene system
Abstract
Hexahydro-2-methylisoquinolines containing a conjugated diene system have been synthesised by isomerisation of 1,2,3,4,5,8-hexahydro-2-methylisoquinolines formed by Birch reduction of 1,2,3,4-tetrahydro-2-methylisoquinoline, 1,2,3,4-tetrahydro-6-methoxy-2-methylisoquinoline, and 1,2,3,4-tetrahydro-7-methoxy-2-methylisoquinoline.
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