Jump to main content
Jump to site search

Issue 21, 1975
Previous Article Next Article

Stereoselective complex formation between simple dipeptides and hydrogen and copper(II) ions

Abstract

Formation constants for the various complexes formed between H+ and Cu2+ and some dipeptides containing amino-acid residues of differing optical hands (Gly-Val, Gly-Phe, and Leu-Leu) have been measured at 25 °C and I= 0.10M(K[NO3]). There is no stereoselectivity when only one of the amino-acids is optically active. When both residues contain asymmetric centres there is no significant stereoselectivity in the complexes formed prior to ionization of the amide hydrogen ion, but it is significant once ionization has taken place. Dipeptide complexes containing amino-acid residues of the same chirality {e.g.[Cu(L-Leu-L-Leu)]} are more stable than those formed by racemic dipeptides {e.g.[Cu(L-Leu-D-Leu)]}.

Back to tab navigation

Article information


J. Chem. Soc., Dalton Trans., 1975, 2302-2304
Article type
Paper

Stereoselective complex formation between simple dipeptides and hydrogen and copper(II) ions

G. Brookes and L. D. Pettit, J. Chem. Soc., Dalton Trans., 1975, 2302
DOI: 10.1039/DT9750002302

Search articles by author

Spotlight

Advertisements