Four tetrapeptides, Tyr-Gly-Gly-Tyr, Tyr-Gly-Tyr-Gly, Gly-Tyr-Gly-Tyr, and Gly-Tyr-Tyr-Gly, together with intermediate dipeptides, have been synthesised using the o-nitrophenylthio-group for N-protection and NN′-dicyclohexylcarbodi-imide–2,4,5-trichlorophenol for coupling reactions.
J. Al-Hassan, J. S. Davies and C. H. Hassall, J. Chem. Soc., Perkin Trans. 1, 1974, 2342 DOI: 10.1039/P19740002342
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